CKDdb-logoCKDdb - Molecule ID A834B

geneARF6
nameADP-ribosylation factor 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ARF6_HUMANP62330ENSG00000165527382Hs.525330600464

Functions and classifications

GOC:cell cortex, C:cleavage furrow, C:early endosome, C:endocytic vesicle, C:filopodium membrane, C:Golgi apparatus, C:midbody, C:recycling endosome membrane, C:ruffle, F:GTP binding, F:GTPase activity, P:cell adhesion, P:cell cycle, P:cell division, P:cellular component movement, P:cortical actin cytoskeleton organization, P:establishment of epithelial cell polarity, P:hepatocyte apoptotic process, P:liver development, P:myeloid cell apoptotic process, P:negative regulation of receptor-mediated endocytosis, P:positive regulation of actin filament polymerization, P:positive regulation of establishment of protein localization to plasma membrane, P:protein localization to cell surface, P:protein localization to endosome, P:protein transport, P:regulation of dendritic spine development, P:regulation of filopodium assembly, P:regulation of Rac protein signal transduction, P:ruffle organization, P:small GTPase mediated signal transduction, P:vesicle-mediated transport, C:intracellular, C:endosome, C:endosome membrane, C:recycling endosome, P:apoptotic process
UniProt3D-structure, Cell cycle, Cell division, Cell membrane, Cell projection, Complete proteome, Cytoplasm, Differentiation, Endosome, ER-Golgi transport, Golgi apparatus, GTP-binding, Lipoprotein, Membrane, Myristate, Neurogenesis, Nucleotide-binding, Protein transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.360.0221671RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.430.0000233RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)3.110.000191RNA microarray19698090
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)2.15< 0.05LC-MS/MS19845401
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.897.14E-06RNA microarray20019191

Compile date 08-10-2018© iMODE-CKD consortium