CKDdb-logoCKDdb - Molecule ID A828B

geneAQP5
nameAquaporin 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AQP5_HUMANP55064ENSG00000161798362Hs.298023600231, 600442

Functions and classifications

GOC:apical plasma membrane, C:basal plasma membrane, C:endoplasmic reticulum, C:integral component of plasma membrane, C:microvillus, F:water channel activity, P:camera-type eye morphogenesis, P:carbon dioxide transport, P:excretion, P:odontogenesis, P:pancreatic juice secretion, P:saliva secretion, C:integral to plasma membrane
UniProt3D-structure, Complete proteome, Disease mutation, Glycoprotein, Membrane, Palmoplantar keratoderma, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.120.00000317RNA microarray19698090
Exp23291264aRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)0.430.0057099RNA microarray23291264
Exp23757392cRattus norvegicus18kidneywholeDiabetes (diabetic nephropathy)5.97< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium