CKDdb-logoCKDdb - Molecule ID A826B

geneAQP3
nameAquaporin 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AQP3_HUMANQ92482ENSG00000165272360Hs.234642600170, 607457

Functions and classifications

GOC:basolateral plasma membrane, C:cell-cell junction, C:cytoplasm, C:integral component of membrane, C:plasma membrane, F:glycerol channel activity, F:water channel activity, P:excretion, P:odontogenesis, P:positive regulation of immune system process, P:regulation of keratinocyte differentiation, P:renal water absorption, P:response to calcium ion, P:response to retinoic acid, P:response to vitamin D, P:urea transport, F:transporter activity, C:integral to membrane
UniProtAlternative splicing, Blood group antigen, Cell membrane, Complete proteome, Glycoprotein, Membrane, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)3.835.24E-05NGS, RNA-seq.22266139
Exp24761003dRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.8< 0.05LC-MS/MS24761003
Exp24761003eRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.77< 0.05LC-MS/MS24761003
Exp24761003fRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy)0.46< 0.05LC-MS/MS24761003
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.833.44E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)12.820.012657RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium