CKDdb-logoCKDdb - Molecule ID A819B

geneAPOL3
nameApolipoprotein L3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APOL3_HUMANO95236ENSG0000012828480833Hs.474737607253

Functions and classifications

GOC:cytoplasm, C:extracellular region, F:lipid binding, F:lipid transporter activity, F:signal transducer activity, P:inflammatory response, P:lipoprotein metabolic process, P:positive regulation of I-kappaB kinase/NF-kappaB signaling, P:positive regulation of I-kappaB kinase/NF-kappaB cascade
UniProtAlternative splicing, Complete proteome, Cytoplasm, Lipid transport, Polymorphism, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.273.23E-06RNA microarray20019191
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.480.014326738NGS, RNA-seq.22266139
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)2.37< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium