CKDdb-logoCKDdb - Molecule ID A815B

geneAPOD
nameApolipoprotein D precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
APOD_HUMANP05090ENSG00000189058347Hs.522555107740

Functions and classifications

GOC:cytosolic ribosome, C:dendrite, C:endoplasmic reticulum, C:extracellular space, C:neuronal cell body, C:perinuclear region of cytoplasm, F:cholesterol binding, F:lipid transporter activity, P:aging, P:angiogenesis, P:brain development, P:glucose metabolic process, P:lipid metabolic process, P:negative regulation of cytokine production involved in inflammatory response, P:negative regulation of focal adhesion assembly, P:negative regulation of lipoprotein lipid oxidation, P:negative regulation of monocyte chemotactic protein-1 production, P:negative regulation of platelet-derived growth factor receptor signaling pathway, P:negative regulation of protein import into nucleus, P:negative regulation of smooth muscle cell proliferation, P:negative regulation of smooth muscle cell-matrix adhesion, P:negative regulation of T cell migration, P:peripheral nervous system axon regeneration, P:response to drug, P:response to reactive oxygen species, P:tissue regeneration, C:extracellular region, F:lipid binding, F:transporter activity, F:small molecule binding, C:intracellular
UniProt3D-structure, Complete proteome, Direct protein sequencing, Disulfide bond, Glycoprotein, Lipid-binding, Polymorphism, Pyrrolidone carboxylic acid, Reference proteome, Secreted, Signal, Transport, Lipoprotein
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp15042541Homo sapiens4kidneyglomeruliDiabetes (diabetic nephropathy)0.15< 0.01RNA microarray15042541
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.360.0073686RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.00000542RNA microarray19698090
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp20639044aHomo sapiens46urinewholeureteral_obstruction (unilateral uteropelvic junction obstruction)29.61< 0.05LC-MS/MS20639044
Exp20639044bHomo sapiens46urinewholeureteral_obstruction (unilateral uteropelvic junction obstruction)6.85< 0.05LC-MS/MS20639044
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.03< 0.05RNA microarray21752957
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)0.460.00013LC-MS/MS23228063
Exp23464927Homo sapiens10urine Fabry (12 months of ERT)1<0.05QTOF MS/MS23464927
Exp24067438Homo sapiens64urinewholeAKI (AKI)8.57< 0.05LC-ESI-MS/MS24067438
Exp24211404Homo sapiens16urineexosomeDiabetes (diabetic nephropathy)0.160.00069LC-MS/MS24211404
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome)3.58.30E-11LC-MS25150443
Exp25957429Homo sapiens21urinewholeGlomerulonephritis (IgA nephropathy)0.15<0.05nano-LC-MS/MS25957429

Compile date 08-10-2018© iMODE-CKD consortium