CKDdb-logoCKDdb - Molecule ID A7979

geneAcaa2
name3-ketoacyl-CoA thiolase, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
THIM_MOUSEQ8BWT1ENSMUSG0000003688052538Mm.245724

Functions and classifications

GOC:mitochondrial inner membrane, C:mitochondrion, F:acetyl-CoA C-acyltransferase activity, P:fatty acid metabolic process, P:negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
UniProtAcetylation, Acyltransferase, Complete proteome, Fatty acid metabolism, Lipid metabolism, Mitochondrion, Phosphoprotein, Reference proteome, Transferase, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model) 2.330.05RNA microarray  17579666
Exp17609286Mus musculus10kidneyglomeruliDiabetes (diabetic nephropathy in Type 1 diabetes) up< 0.05MALDI-TOF-MS  17609286
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.40.02cDNA microarray  19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.460cDNA microarray  19099603
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model) 0.480.015589658LC-MS/MS  24316357
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)   LC-MS/MS  24726496
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)   LC-MS/MS  24726496
Exp24726496Rattus norvegicus kidneyglomeruliDiabetes (diabetic nephropathy)   LC-MS/MS  24726496

Compile date 08-30-2016© iMODE-CKD consortium