CKDdb-logoCKDdb - Molecule ID A796G

geneA-C1, HRASLS, HSD28
namePhospholipid-metabolizing enzyme A-C1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
HRSL1_HUMANQ9HDD0ENSG0000012725257110Hs.36761606487

Functions and classifications

GOC:integral component of membrane, C:nuclear envelope lumen, C:peroxisome, F:phospholipase activity, F:transferase activity, P:ether lipid metabolic process, P:lipid catabolic process, P:peroxisome organization, C:cytoplasm, C:integral to membrane, F:hydrolase activity
UniProtComplete proteome, Hydrolase, Lipid degradation, Lipid metabolism, Membrane, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)0.370.048499RNA microarray19698090
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease)2.280.0113036RNA microarray19698090
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.45< 0.05RNA-seq23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)0.18< 0.05RNA-seq23757392
Exp23757392cRattus norvegicus18kidneywholeDiabetes (diabetic nephropathy)2.41< 0.05RNA-seq23757392
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.413.31E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium