CKDdb-logoCKDdb - Molecule ID A795B

geneAfm
nameAfamin
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AFAM_MOUSEO89020ENSMUSG00000029369280662Mm.348786104145

Functions and classifications

GOC:extracellular space, F:vitamin E binding, P:vitamin transport
UniProtAlternative splicing, Complete proteome, Disulfide bond, Glycoprotein, Reference proteome, Repeat, Secreted, Signal, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionValidationPubMed/DOI
Exp17301227Homo sapiens13bloodserumFabry (6 months of ERT) 0.064nanoLC-ESI-MS/MS 17301227
Exp17579666cMus musculus6 to 12kidneywholeremnant_kidney_model (remnant kidney model)2.40.05RNA microarray 17579666
Exp18440303Rattus norvegicus20urineglycoproteinsGlomerulonephritis (adriamycin nephropathy and Thy1.1 induced glomerulonephritis)1.81 LC-MS/MS 18440303
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.390cDNA microarray 19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.390cDNA microarray 19099603
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.193.23E-06RNA microarray 20019191
Exp20411046Homo sapiens5kidneycyst fluidPolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease) < 0.001LC-MS/MS 20411046
Exp21544065aRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)0.550.023MALDI-TOF/TOF 21544065
Exp21544065cRattus norvegicus17kidney Diabetes (diabetic nephropathy in T1D)0.560.035MALDI-TOF/TOF 21544065
Exp22536212Homo sapiens86urinewholeDiabetes (type 2 diabetic nephropathy)4.670hybrid quadrupole-TOF, LC-MS/MS 22536212
Exp22891811aHomo sapiens10urinewholeureteral_obstruction (congenital bilateral hydronephrosis)0.72 +/- 0.015 < 0.05LC-MS/MS 22891811
Exp22891811bHomo sapiens10urinewholeureteral_obstruction (congenital bilateral hydronephrosis)0.63 +/- 0.044< 0.05LC-MS/MS 22891811
Exp23228063Homo sapiens30urinewholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic Kidney disease)1.70.00003LC-MS/MS 23228063
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.23< 0.05RNA-seq 23757392
Exp23757392bRattus norvegicus13kidneywholeDiabetes (diabetic nephropathy)0.3< 0.05RNA-seq 23757392
Exp24339887Homo sapiens13urinewholeGlomerulonephritis (IgA nephropathy)1.8< 0.05GeLC-MS/MS 24339887
Exp25032130Homo sapiens11urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)0.61 nano-flow LC-MS/MS 25032130
Exp25619383Homo sapiens46bloodplasmaFabry (Fabry) 0LC-MS/MSMRM25619383
Exp25666440Homo sapiens23urinesupernatantFabry (naive Fabry patients)3.570.027293nanoLC-ESI-MS/MS 25666440
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)15.910.013999RNA microarray 26317775

Compile date 08-10-2018© iMODE-CKD consortium