CKDdb-logoCKDdb - Molecule ID A7851

geneAGMAT
nameAgmatinase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
SPEB_HUMANQ9BSE5ENSG0000011677179814Hs.461532

Functions and classifications

GOC:mitochondrion, F:agmatinase activity, F:metal ion binding, P:agmatine biosynthetic process, P:polyamine metabolic process, P:putrescine biosynthetic process from arginine, P:small molecule metabolic process, P:spermidine biosynthetic process
UniProtAcetylation, Complete proteome, Hydrolase, Manganese, Metal-binding, Mitochondrion, Polymorphism, Putrescine biosynthesis, Reference proteome, Spermidine biosynthesis, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.310.00199RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.261.98E-05RNA microarray20019191
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.279.90E-04Nano RP-LC, MALDI-TOF22061828
Exp23760282bMus musculus kidneywholeureteral_obstruction (renal tubulointerstitial injury)0.350.025RNA microarray23760282

Compile date 08-10-2018© iMODE-CKD consortium