CKDdb-logoCKDdb - Molecule ID A782B

geneABCD4, PXMP1L
nameATP-binding cassette
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCD4_HUMANO14678ENSG000001196885826Hs.94395603214, 614857

Functions and classifications

GOC:ATP-binding cassette (ABC) transporter complex, C:endoplasmic reticulum membrane, C:integral component of membrane, C:peroxisomal membrane, C:peroxisome, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:cobalamin metabolic process, F:ATPase activity, P:ATP catabolic process, C:integral component of membrane, P:ATP catabolic process, C:membrane, P:transport, C:integral to membrane, C:integral to membrane
UniProtATP-binding, Complete proteome, Disease mutation, Membrane, Nucleotide-binding, Peroxisome, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.480.04cDNA microarray  19099603
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease) 2.020.0234455RNA microarray  19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.370.013RNA microarray  19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 3.230.0000411RNA microarray  19698090
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease) 0.450.0417785RNA microarray  23935909

Compile date 08-30-2016© iMODE-CKD consortium