CKDdb-logoCKDdb - Molecule ID A781B

geneABCD2, ALD1, ALDL1
nameATP-binding cassette
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCD2_HUMANQ9UBJ2ENSG00000173208225Hs.117852601081

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:mitochondrion, C:peroxisomal membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:protein homodimerization activity, P:ATP catabolic process, P:fatty acid beta-oxidation, P:positive regulation of fatty acid beta-oxidation, P:transmembrane transport, P:very long-chain fatty acid catabolic process, C:cytosol, C:integral to membrane, F:ATPase activity, P:very long-chain fatty acid catabolic process
UniProtATP-binding, Complete proteome, Glycoprotein, Membrane, Nucleotide-binding, Peroxisome, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090aHomo sapiens17bloodmononuclear cellsChronic_Renal_Insufficiency (Chronic kidney disease) 0.290.0088541RNA microarray  19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.370.0208RNA microarray  19698090
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy) 0.469.69E-05NGS, RNA-seq.  22266139
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease) 0.390.047373RNA microarray  23935909

Compile date 08-30-2016© iMODE-CKD consortium