CKDdb-logoCKDdb - Molecule ID A780B

geneALD, ABCD1, ALDP
nameAdrenoleukodystrophy protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCD1_HUMANP33897ENSG00000101986215Hs.159546300100, 300371, 300475

Functions and classifications

GOC:cytosol, C:integral component of peroxisomal membrane, C:mitochondrion, C:perinuclear region of cytoplasm, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, F:peroxisomal fatty-acyl-CoA transporter activity, F:protein homodimerization activity, P:alpha-linolenic acid metabolic process, P:fatty acid beta-oxidation using acyl-CoA oxidase, P:linoleic acid metabolic process, P:long-chain fatty acid catabolic process, P:peroxisomal membrane transport, P:peroxisome organization, P:very long-chain fatty acid catabolic process, F:ATPase activity, P:ATP catabolic process, C:membrane, P:transport, C:integral to peroxisomal membrane
UniProtATP-binding, Complete proteome, Disease mutation, Glycoprotein, Membrane, Nucleotide-binding, Peroxisome, Phosphoprotein, Reference proteome, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.350.00379RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.50.00105RNA microarray19698090
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.152.72E-09RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium