CKDdb-logoCKDdb - Molecule ID A7774

geneAHCYL1, DCAL, XPVKONA
nameAdenosylhomocysteinase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
SAHH2_HUMANO43865ENSG0000016871010768Hs.743973607826

Functions and classifications

GOC:endoplasmic reticulum, F:adenosylhomocysteinase activity, P:mRNA polyadenylation, P:one-carbon metabolic process, P:positive regulation of sodium ion transport, P:protein export from nucleus, P:regulation of anion transport, P:regulation of ion transmembrane transporter activity, P:regulation of mRNA 3'-end processing, F:nucleotide binding
UniProt3D-structure, Acetylation, Alternative splicing, Complete proteome, Endoplasmic reticulum, Hydrolase, NAD, One-carbon metabolism, Phosphoprotein, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.280.00000511RNA microarray19698090
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy)3.64< 0.05LC-MS/MS19845401
Exp24172336Mus musculus6kidneycortexAKI (AKI)1.230.047822241LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium