CKDdb-logoCKDdb - Molecule ID A773B

geneABCA12, ABC12
nameATP-binding cassette transporter family A member 12
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCAC_HUMANQ86UK0ENSG0000014445226154Hs.134585242500, 601277, 607800, 242100

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:mitochondrial inner membrane, F:ATP binding, F:ATPase activity, P:ATP catabolic process, P:cellular homeostasis, P:ceramide transport, P:establishment of skin barrier, P:keratinization, P:lipid homeostasis, P:lipid transport, P:lung alveolus development, P:surfactant homeostasis, C:integral to membrane
UniProtAlternative splicing, ATP-binding, Complete proteome, Disease mutation, Glycoprotein, Ichthyosis, Membrane, Nucleotide-binding, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy) 1.40.001cDNA microarray  23505438
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 0.140.014471RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium