CKDdb-logoCKDdb - Molecule ID A771B

geneAbca8b, Abca8
nameATP-binding cassette sub-family A member 8-B
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABC8B_MOUSEQ8K440ENSMUSG0000002062027404Mm.341004612505

Functions and classifications

GOC:integral component of membrane, C:mitochondrial inner membrane, C:plasma membrane, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, C:integral to membrane, P:ATP catabolic process
UniProtAlternative splicing, ATP-binding, Cell membrane, Complete proteome, Glycoprotein, Membrane, Nucleotide-binding, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease) 0.310.01cDNA microarray  19099603
Exp19845401Mus musculus32eyesretinaDiabetes (diabetic retinopathy) 2.23< 0.05LC-MS/MS  19845401
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 8.76< 0.05RNA microarray  21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI) 1.490.004063539LC-MS/MS  24172336

Compile date 08-30-2016© iMODE-CKD consortium