CKDdb-logoCKDdb - Molecule ID A770B

geneABCA7, ABCA7/ABCA-SSN
nameATP-binding cassette sub-family A member 7
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCA7_HUMANQ8IZY2ENSG0000006468710347Hs.134514605414

Functions and classifications

GOC:apical plasma membrane, C:ATP-binding cassette (ABC) transporter complex, C:endosome membrane, C:Golgi apparatus, C:Golgi membrane, C:integral component of membrane, F:ATP binding, F:ATPase activity, F:phospholipid transporter activity, F:transporter activity, P:ATP catabolic process, P:phagocytosis, P:phospholipid efflux, P:transmembrane transport, C:intracellular, C:integral to membrane, C:plasma membrane
UniProtAlternative splicing, ATP-binding, Cell membrane, Complete proteome, Disulfide bond, Endosome, Glycoprotein, Golgi apparatus, Membrane, Nucleotide-binding, Phagocytosis, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.490.000013RNA microarray  19698090
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy) 0.720.031cDNA microarray  23505438
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 3.890.011393RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium