CKDdb-logoCKDdb - Molecule ID A7668

geneADARB1, hRED1, ADAR2d
nameRNA-specific adenosine deaminase B1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
RED1_HUMANP78563ENSG00000197381104Hs.474018601218

Functions and classifications

GOC:nucleolus, C:nucleoplasm, C:nucleus, F:adenosine deaminase activity, F:double-stranded RNA adenosine deaminase activity, F:double-stranded RNA binding, F:metal ion binding, F:mRNA binding, F:RNA binding, P:adenosine to inosine editing, P:base conversion or substitution editing, P:defense response to virus, P:gene expression, P:innate immune response, P:mRNA modification, P:mRNA processing, P:negative regulation of cell migration, P:negative regulation of cell proliferation, P:negative regulation of protein kinase activity by regulation of protein phosphorylation, P:positive regulation of viral genome replication, P:regulation of cell cycle, P:RNA processing, C:intracellular
UniProt3D-structure, Alternative splicing, Antiviral defense, Complete proteome, Hydrolase, Immunity, Innate immunity, Metal-binding, mRNA processing, Nucleus, Phosphoprotein, Reference proteome, Repeat, RNA-binding, Zinc
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.00002RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.350.000167RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.783.23E-06RNA microarray20019191
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)3.39< 0.05RNA microarray21752957
Exp23809614aHomo sapiens83bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)4.598.38E-16RNA microarray23809614
Exp23809614bHomo sapiens32bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)7.311.24E-12RNA microarray23809614

Compile date 08-10-2018© iMODE-CKD consortium