CKDdb-logoCKDdb - Molecule ID A765B

geneABCA2, ABC2
nameATP-binding cassette
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
ABCA2_HUMANQ9BZC7ENSG0000010733120Hs.421202600047

Functions and classifications

GOC:ATP-binding cassette (ABC) transporter complex, C:cytoplasmic membrane-bounded vesicle, C:endosome, C:endosome membrane, C:integral component of membrane, C:lysosomal membrane, C:lysosome, C:microtubule organizing center, F:ATP binding, F:ATPase activity, coupled to transmembrane movement of substances, P:cholesterol homeostasis, P:lipid metabolic process, P:regulation of intracellular cholesterol transport, P:regulation of transcription from RNA polymerase II promoter, P:response to drug, P:response to steroid hormone, F:ATPase activity, P:ATP catabolic process, C:integral to membrane, P:response to steroid hormone stimulus
UniProtAlternative splicing, ATP-binding, Complete proteome, Endosome, Glycoprotein, Lysosome, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Repeat, Transmembrane, Transmembrane helix, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.420.0342RNA microarray  19698090
Exp24172336Mus musculus6kidneycortexAKI (AKI) 10000.018792802LC-MS/MS  24172336

Compile date 08-30-2016© iMODE-CKD consortium