CKDdb-logoCKDdb - Molecule ID A7559

nameAdenylosuccinate synthetase isozyme 1
speciesHomo sapiens

Molecule reference


Functions and classifications

GOC:cytosol, F:adenylosuccinate synthase activity, F:GTP binding, F:GTPase activity, F:magnesium ion binding, F:phosphate ion binding, P:'de novo' AMP biosynthetic process, P:AMP biosynthetic process, P:aspartate metabolic process, P:cellular response to drug, P:cellular response to electrical stimulus, P:glutamine metabolic process, P:immune system process, P:IMP metabolic process, P:purine nucleobase metabolic process, P:response to muscle activity, P:response to starvation, P:purine nucleotide biosynthetic process, C:cytoplasm, P:purine ribonucleoside monophosphate biosynthetic process
UniProt3D-structure, Alternative splicing, Complete proteome, Cytoplasm, GTP-binding, Ligase, Magnesium, Metal-binding, Nucleotide-binding, Purine biosynthesis, Reference proteome
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)9.210.009012RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium