CKDdb-logoCKDdb - Molecule ID A7472

geneAcpp
nameProstatic acid phosphatase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPAP_MOUSEQ8CE08ENSMUSG0000003256156318Mm.19941171790

Functions and classifications

GOC:apical part of cell, C:extracellular space, C:filopodium, C:Golgi cisterna, C:integral component of membrane, C:lysosomal membrane, C:multivesicular body, C:plasma membrane, C:secretory granule, C:vesicle membrane, F:5'-nucleotidase activity, F:acid phosphatase activity, F:choline binding, F:lysophosphatidic acid phosphatase activity, F:phosphatase activity, F:thiamine phosphate phosphatase activity, P:adenosine metabolic process, P:dephosphorylation, P:nucleotide metabolic process, P:positive regulation of adenosine receptor signaling pathway, P:purine nucleobase metabolic process, P:regulation of sensory perception of pain, P:thiamine metabolic process, F:acid phosphatase activity, P:dephosphorylation
UniProtAlternative splicing, Cell membrane, Complete proteome, Disulfide bond, Glycoprotein, Hydrolase, Lysosome, Membrane, Reference proteome, Secreted, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp21595033bHomo sapiens14urineexosomesGlomerulonephritis (basement membrane nephropathy) 0.140.00018LC-MS/MS  21595033
Exp23989031aMus musculus kidneycortexGlomerulonephritis (Glomerulonephritis) 2.6< 0.01DNA microarray  23989031
Exp23989031bMus musculus kidneycortexGlomerulonephritis (Glomerulonephritis) 2.9< 0.01DNA microarray  23989031
Exp24096133bHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy) 1000 1DE, MALDI  24096133
Exp24096133cHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy) 1000 1DE, MALDI  24096133
Exp24096133dHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy vs type 1 diabetes without retinopathy or nephropathy) 1000 1DE, MALDI  24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy) 1000 1DE, MALDI  24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy) 6.2 1DE, MALDI  24096133
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 2.130.00000306RNA microarray  24569379
Exp24761003aRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy) 0.61< 0.05LC-MS/MS  24761003
Exp24761003aRattus norvegicus18kidneymedullaureteral_obstruction (obstructive uropathy) 1.2< 0.05LC-MS/MS  24761003
Exp25150443aHomo sapiens24urinesupernatantNephrotic_Syndrome (paediatric idiopathic nephrotic syndrome) 3.95.30E-06LC-MS  25150443

Compile date 08-30-2016© iMODE-CKD consortium