CKDdb-logoCKDdb - Molecule ID A7471

geneAcp2
nameLysosomal acid phosphatase
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPAL_MOUSEP24638ENSMUSG0000000210311432Mm.45570171650, 200950

Functions and classifications

GOC:integral component of membrane, C:lysosomal lumen, C:lysosomal membrane, C:lysosome, F:acid phosphatase activity, P:dephosphorylation, P:lysosome organization, P:skeletal system development, C:cytoplasmic vesicle, C:integral to membrane, F:phosphoprotein phosphatase activity, P:autophagic cell death, P:response to organic substance
UniProtComplete proteome, Disulfide bond, Glycoprotein, Hydrolase, Lysosome, Membrane, Reference proteome, Signal, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis) 4.3< 0.05RNA microarray  18187931
Exp20543976Homo sapiens40urinewholeTransplantation (acute renal allograft rejection) 0.3 LC-MS/MS  20543976
Exp21752957bHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease) 3.41< 0.05RNA microarray  21752957
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy) 1.36 nLC-ESI-UHR-QToF-MS/MS  23344851
Exp24096133cHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy) 1000 1DE, MALDI  24096133
Exp24096133eHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes without retinopathy or nephropathy) 1000 1DE, MALDI  24096133
Exp24096133fHomo sapiens10urine>10kDaDiabetes (type 1 diabetes with retinopathy and nephropathy vs type 1 diabetes with retinopathy) 1000 1DE, MALDI  24096133
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 3.790.013999RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium