CKDdb-logoCKDdb - Molecule ID A7469

geneAcp6, Acpl1, Lpap
nameLysophosphatidic acid phosphatase type 6
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPA6_MOUSEQ8BP40ENSMUSG0000002809366659Mm.101368611471

Functions and classifications

GOC:mitochondrion, F:acid phosphatase activity, F:lysophosphatidic acid phosphatase activity, P:dephosphorylation, P:hematopoietic progenitor cell differentiation, P:lysobisphosphatidic acid metabolic process
UniProtAlternative splicing, Complete proteome, Hydrolase, Lipid metabolism, Mitochondrion, Phospholipid metabolism, Reference proteome, Transit peptide
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies) 8< 0.05cDNA microarrays  17183245
Exp24172336Mus musculus6kidneycortexAKI (AKI) 1.260.047822241LC-MS/MS  24172336
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI) 0.330.00000267RNA microarray  24569379

Compile date 08-30-2016© iMODE-CKD consortium