CKDdb-logoCKDdb - Molecule ID A7468

geneACP5
nameTartrate-resistant acid phosphatase type 5 precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PPA5_HUMANP13686ENSG0000010257554Hs.1211171640, 607944

Functions and classifications

GOC:cytosol, C:integral component of membrane, C:lysosome, F:acid phosphatase activity, F:ferric iron binding, F:ferrous iron binding, P:bone morphogenesis, P:bone resorption, P:defense response to Gram-positive bacterium, P:negative regulation of inflammatory response, P:negative regulation of interleukin-1 beta production, P:negative regulation of interleukin-12 production, P:negative regulation of nitric oxide biosynthetic process, P:negative regulation of superoxide anion generation, P:negative regulation of tumor necrosis factor production, P:response to cytokine, P:response to lipopolysaccharide, P:riboflavin metabolic process, C:integral to membrane, P:response to cytokine stimulus
UniProt3D-structure, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Glycoprotein, Hydrolase, Iron, Lysosome, Metal-binding, Polymorphism, Reference proteome, Signal
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18187931aMus musculus20kidneyglomeruliGlomerulonephritis (lupus nephritis)10.5< 0.05RNA microarray18187931
Exp18187931bMus musculus18kidneyglomeruliGlomerulonephritis (lupus nephritis)7< 0.05RNA microarray18187931
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.550.000226863RNA microarray20019191
Exp21411733aMus musculus13macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)4.020cDNA microarray21411733
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.350cDNA microarray21411733
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.371.05E-22NGS, RNA-seq.22266139

Compile date 08-10-2018© iMODE-CKD consortium