CKDdb-logoCKDdb - Molecule ID A7421

geneAgpat4
name1-acyl-sn-glycerol-3-phosphate acyltransferase delta
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PLCD_MOUSEQ8K4X7ENSMUSG0000002382768262Mm.258300614795

Functions and classifications

GOC:integral component of membrane, F:1-acylglycerol-3-phosphate O-acyltransferase activity, P:CDP-diacylglycerol biosynthetic process, C:integral to membrane, F:transferase activity, transferring acyl groups
UniProtAcyltransferase, Complete proteome, Lipid biosynthesis, Lipid metabolism, Membrane, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.440cDNA microarray21411733
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.170.014123RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium