CKDdb-logoCKDdb - Molecule ID A7420

geneAGPAT3, UNQ759/PRO1490, UNQ759
name1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PLCC_HUMANQ9NRZ7ENSP0000029157256894Hs.248785614794

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, C:nuclear envelope, C:plasma membrane, F:1-acylglycerol-3-phosphate O-acyltransferase activity, P:CDP-diacylglycerol biosynthetic process, P:phosphatidic acid biosynthetic process, P:small molecule metabolic process, P:triglyceride biosynthetic process, F:transferase activity, transferring acyl groups, C:integral to membrane
UniProtAcyltransferase, Alternative splicing, Complete proteome, Endoplasmic reticulum, Lipid biosynthesis, Lipid metabolism, Membrane, Nucleus, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)11.63< 0.05cDNA microarrays17183245
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)0.31< 0.05RNA microarray21752957
Exp24172336Mus musculus6kidneycortexAKI (AKI)2.470.008867947LC-MS/MS24172336

Compile date 08-10-2018© iMODE-CKD consortium