CKDdb-logoCKDdb - Molecule ID A7416

geneAGPAT2
name1-acyl-sn-glycerol-3-phosphate acyltransferase beta
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
PLCB_HUMANO15120ENSG0000016969210555Hs.320151603100, 608594

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:1-acylglycerol-3-phosphate O-acyltransferase activity, P:CDP-diacylglycerol biosynthetic process, P:epidermis development, P:phosphatidic acid biosynthetic process, P:positive regulation of cytokine production, P:positive regulation of cytokine-mediated signaling pathway, P:small molecule metabolic process, P:triglyceride biosynthetic process, C:endoplasmic reticulum, C:membrane, P:phospholipid biosynthetic process, C:integral to membrane
UniProtAcyltransferase, Alternative splicing, Complete proteome, Congenital generalized lipodystrophy, Diabetes mellitus, Disease mutation, Endoplasmic reticulum, Lipid biosynthesis, Lipid metabolism, Membrane, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Signal, Transferase, Transmembrane, Transmembrane helix, Phosphoprotein
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.560.013579RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium