CKDdb-logoCKDdb - Molecule ID A732G

geneCBLL1, HAKAI, RNF188
nameE3 ubiquitin-protein ligase HAKAI
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
HAKAI_HUMANQ75N03ENSG0000010587979872Hs.592271606872

Functions and classifications

GOC:ubiquitin ligase complex, F:ubiquitin-protein ligase activity, F:zinc ion binding, P:cell-cell adhesion, P:negative regulation of cell adhesion, P:positive regulation of cell migration, P:positive regulation of endocytosis, F:nucleic acid binding, P:protein ubiquitination, F:metal ion binding, C:intracellular
UniProtComplete proteome, Ligase, Metal-binding, Phosphoprotein, Reference proteome, Ubl conjugation pathway, Zinc, Zinc-finger
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.444.16E-06RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium