CKDdb-logoCKDdb - Molecule ID A7227

geneBckdha
name2-oxoisovalerate dehydrogenase subunit alpha
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
ODBA_RATP11960ENSRNOG0000002060725244Rn.49145

Functions and classifications

GOC:mitochondrial alpha-ketoglutarate dehydrogenase complex, C:mitochondrion, F:2-oxoisovalerate dehydrogenase (acylating) activity, F:3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity, F:alpha-ketoacid dehydrogenase activity, F:metal ion binding, F:protein complex binding, P:branched-chain amino acid catabolic process, P:response to cAMP, P:response to glucocorticoid, P:response to nutrient, P:response to glucocorticoid stimulus, C:mitochondrion, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, C:mitochondrial alpha-ketoglutarate dehydrogenase complex, F:alpha-ketoacid dehydrogenase activity, P:branched-chain amino acid catabolic process, C:mitochondrion, F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor, C:mitochondrial alpha-ketoglutarate dehydrogenase complex, F:alpha-ketoacid dehydrogenase activity, P:branched-chain amino acid catabolic process
UniProtAcetylation, Complete proteome, Metal-binding, Mitochondrion, Oxidoreductase, Phosphoprotein, Potassium, Reference proteome, Thiamine pyrophosphate, Transit peptide, Complete proteome, Reference proteome,
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesTissue / SourceDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp22061828Rattus norvegicuskidneyGentamicin_induced (Gentamicin-induced nephropathy)0.361.40E-06Nano RP-LC, MALDI-TOF22061828

Compile date 08-10-2018© iMODE-CKD consortium