CKDdb-logoCKDdb - Molecule ID A6998

geneMEP1B
nameMeprin A subunit beta
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
MEP1B_HUMANQ16820ENSG000001414344225Hs.194777600389

Functions and classifications

GOC:extracellular space, C:integral component of plasma membrane, F:metalloendopeptidase activity, F:zinc ion binding, P:digestion, P:inflammatory response, P:proteolysis, C:integral to plasma membrane, F:metal ion binding, C:membrane
UniProt3D-structure, Cell membrane, Complete proteome, Direct protein sequencing, Disulfide bond, EGF-like domain, Glycoprotein, Hydrolase, Inflammatory response, Membrane, Metal-binding, Metalloprotease, Polymorphism, Protease, Reference proteome, Secreted, Signal, Transmembrane, Transmembrane helix, Zinc, Zymogen
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.310cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.420.0119RNA microarray19698090
Exp23344851Rattus norvegicus14urineexosomeDiabetes (diabetic nephropathy)0.49 nLC-ESI-UHR-QToF-MS/MS23344851
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.140.0000154RNA microarray24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.281.75E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium