CKDdb-logoCKDdb - Molecule ID A698H

geneBGLAP
nameOsteocalcin precursor
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
OSTCN_HUMANP02818ENSP00000357255632Hs.654541112260

Functions and classifications

GOC:dendrite, C:extracellular region, C:extracellular space, C:Golgi apparatus, C:membrane-bounded vesicle, C:perikaryon, C:rough endoplasmic reticulum, F:calcium ion binding, F:hydroxyapatite binding, F:structural constituent of bone, P:bone development, P:bone mineralization, P:cell adhesion, P:cell aging, P:cellular response to growth factor stimulus, P:cellular response to vitamin D, P:odontogenesis, P:osteoblast development, P:osteoblast differentiation, P:regulation of bone mineralization, P:regulation of bone resorption, P:regulation of osteoclast differentiation, P:response to activity, P:response to drug, P:response to estrogen, P:response to ethanol, P:response to glucocorticoid, P:response to gravity, P:response to hydroxyisoflavone, P:response to mechanical stimulus, P:response to testosterone, P:response to vitamin D, P:response to vitamin K, P:response to zinc ion, P:skeletal system development, C:cell projection, P:response to estrogen stimulus, P:response to glucocorticoid stimulus, P:response to testosterone stimulus
UniProtBiomineralization, Calcium, Cleavage on pair of basic residues, Complete proteome, Direct protein sequencing, Disulfide bond, Gamma-carboxyglutamic acid, Metal-binding, Polymorphism, Reference proteome, Secreted, Signal
PADBCS: Cell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.073.23E-06RNA microarray20019191

Compile date 08-10-2018© iMODE-CKD consortium