CKDdb-logoCKDdb - Molecule ID A6906

geneAATK, AATYK, LMR1
nameSerine/threonine-protein kinase LMTK1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
LMTK1_HUMANQ6ZMQ8ENSG000001814099625Hs.514575605276

Functions and classifications

GOC:axonal growth cone, C:endoplasmic reticulum, C:integral component of membrane, C:mitochondrion, C:perinuclear region of cytoplasm, C:recycling endosome, F:ATP binding, F:protein serine/threonine kinase activity, F:protein tyrosine kinase activity, P:brain development, P:negative regulation of axon extension, P:neuron apoptotic process, P:peptidyl-tyrosine autophosphorylation, P:Rab protein signal transduction, C:integral to membrane, P:apoptotic process, P:protein autophosphorylation
UniProtAlternative splicing, ATP-binding, Complete proteome, Cytoplasm, Kinase, Membrane, Nucleotide-binding, Phosphoprotein, Polymorphism, Reference proteome, Serine/threonine-protein kinase, Transferase, Transmembrane, Transmembrane helix
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseBiomarkerFold change in diseaseP-valueDetectionMol. modificationValidationPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis) 0.21.49E-09RNA microarray  19698090
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 5.449.73E-04RNA microarray  26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD) 3.940.013999RNA microarray  26317775

Compile date 08-30-2016© iMODE-CKD consortium