CKDdb-logoCKDdb - Molecule ID A6837

geneCamk1
nameCalcium/calmodulin-dependent protein kinase type 1
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KCC1A_MOUSEQ91YS8ENSMUSG0000003027252163Mm.277373604998

Functions and classifications

GOC:calcium- and calmodulin-dependent protein kinase complex, C:cytoplasm, C:nucleus, F:ATP binding, F:calmodulin-dependent protein kinase activity, F:protein binding, P:cell cycle, P:nucleocytoplasmic transport, P:positive regulation of dendritic spine development, P:positive regulation of muscle cell differentiation, P:positive regulation of neuron projection development, P:positive regulation of protein export from nucleus, P:positive regulation of protein serine/threonine kinase activity, P:positive regulation of synapse structural plasticity, P:protein phosphorylation, P:regulation of muscle cell differentiation, P:regulation of protein binding, P:regulation of protein localization, P:signal transduction, F:ATP binding, F:protein binding, F:protein serine/threonine kinase activity, P:nucleocytoplasmic transport, P:positive regulation of protein export from nucleus, P:protein phosphorylation, P:signal transduction
UniProtAllosteric enzyme, ATP-binding, Calmodulin-binding, Cell cycle, Complete proteome, Cytoplasm, Developmental protein, Differentiation, Isopeptide bond, Kinase, Neurogenesis, Nucleotide-binding, Nucleus, Phosphoprotein, Reference proteome, Serine/threonine-protein kinase, Transferase, Ubl conjugation
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)2.993.23E-06RNA microarray20019191
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.20.000000223RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium