CKDdb-logoCKDdb - Molecule ID A6829

geneCcbl2, Kat3
nameKynurenine--oxoglutarate transaminase 3
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAT3_MOUSEQ71RI9ENSMUSG00000040213229905Mm.289643610656

Functions and classifications

GOC:mitochondrion, F:cysteine-S-conjugate beta-lyase activity, F:kynurenine-glyoxylate transaminase activity, F:kynurenine-oxoglutarate transaminase activity, F:protein homodimerization activity, F:pyridoxal phosphate binding, P:2-oxoglutarate metabolic process, P:biosynthetic process, P:cellular amino acid metabolic process, P:kynurenine metabolic process, P:L-kynurenine metabolic process, C:mitochondrion
UniProt3D-structure, Acetylation, Alternative splicing, Aminotransferase, Complete proteome, Lyase, Pyridoxal phosphate, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.440cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.40cDNA microarray19099603
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.420.00624RNA microarray24569379

Compile date 08-10-2018© iMODE-CKD consortium