CKDdb-logoCKDdb - Molecule ID A6826

geneAK5
nameAdenylate kinase 5
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAD5_HUMANQ9Y6K8ENSG0000015402726289Hs.559718608009

Functions and classifications

GOC:centrosome, C:cytosol, F:adenylate kinase activity, F:ATP binding, F:nucleoside diphosphate kinase activity, F:nucleoside kinase activity, P:ADP biosynthetic process, P:ATP metabolic process, P:dADP biosynthetic process, P:nucleobase-containing small molecule interconversion, P:nucleoside triphosphate biosynthetic process, P:pyrimidine ribonucleotide biosynthetic process, F:nucleobase-containing compound kinase activity, P:nucleobase-containing compound metabolic process, P:phosphorylation, F:cAMP-dependent protein kinase regulator activity, P:signal transduction
UniProt3D-structure, Alternative splicing, ATP-binding, Complete proteome, Cytoplasm, Kinase, Nucleotide-binding, Polymorphism, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp16372274Homo sapiens25urinewholeGlomerulonephritis (IgA nephropathy)0.05< 0.05MALDI-TOF-MS16372274
Exp22266139Homo sapiens kidneyproximal tubule epithelial cellsDiabetes (diabetic nephropathy)0.491.74E-09NGS, RNA-seq.22266139
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)2.990.0446308RNA microarray23935909
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.38.88E-04RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.140.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium