CKDdb-logoCKDdb - Molecule ID A6824

geneAk3
nameGTP:AMP phosphotransferase AK3, mitochondrial
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAD3_MOUSEQ9WTP7ENSMUSG0000002478256248Mm.196067609290

Functions and classifications

GOC:mitochondrial matrix, C:mitochondrion, F:adenylate kinase activity, F:ATP binding, F:GTP binding, F:nucleoside triphosphate adenylate kinase activity, P:AMP metabolic process, P:GTP metabolic process, P:ITP metabolic process, P:UTP metabolic process
UniProtAcetylation, Complete proteome, GTP-binding, Kinase, Mitochondrion, Nucleotide-binding, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp22970174Mus musculus8kidneywholeChronic_Renal_Insufficiency (mouse_CKD_model)0.37< 0.05RNA microarray22970174
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.47< 0.05RNA-seq23757392

Compile date 08-10-2018© iMODE-CKD consortium