CKDdb-logoCKDdb - Molecule ID A6823

geneAK2, ADK2
nameAdenylate kinase 2
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAD2_HUMANP54819ENSG00000004455204Hs.470907103020, 267500

Functions and classifications

GOC:cytosol, C:mitochondrial inner membrane, C:mitochondrial intermembrane space, C:sperm mitochondrial sheath, F:adenylate kinase activity, F:ATP binding, P:ADP biosynthetic process, P:AMP metabolic process, P:ATP metabolic process, P:brain development, P:dATP metabolic process, P:liver development, P:nucleobase-containing small molecule interconversion, P:oxidative phosphorylation, P:response to thyroid hormone, F:nucleobase-containing compound kinase activity, P:nucleobase-containing compound metabolic process, P:nucleotide phosphorylation, P:AMP salvage
UniProt3D-structure, Acetylation, Alternative splicing, ATP-binding, Complete proteome, Direct protein sequencing, Disease mutation, Disulfide bond, Kinase, Mitochondrion, Nucleotide-binding, Polymorphism, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp18850734Canis lupus familiaris kidneydistal renal tubular cellskidney_calculi (Calcium oxalate monohydrate in vitro model)1.780.021Q-TOF MS/MS18850734
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.330.0000141RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)2.80.000376RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium