CKDdb-logoCKDdb - Molecule ID A6822

geneAK1
nameAdenylate kinase isoenzyme 1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
KAD1_HUMANP00568ENSG00000106992203Hs.175473103000, 612631

Functions and classifications

GOC:cytosol, C:outer dense fiber, C:plasma membrane, C:sperm flagellum, F:adenylate kinase activity, F:ATP binding, F:nucleoside diphosphate kinase activity, P:ATP metabolic process, P:cell cycle arrest, P:nucleobase-containing small molecule interconversion, P:nucleoside triphosphate biosynthetic process, C:cytoplasm, F:nucleobase-containing compound kinase activity, P:nucleobase-containing compound metabolic process, P:nucleoside diphosphate phosphorylation, P:phosphorylation, P:AMP salvage
UniProt3D-structure, Acetylation, ATP-binding, Complete proteome, Cytoplasm, Direct protein sequencing, Disease mutation, Hereditary hemolytic anemia, Kinase, Nucleotide-binding, Polymorphism, Reference proteome, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.190.000539RNA microarray19698090
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.340.00429RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.273.23E-06RNA microarray20019191
Exp23192593Rattus norvegicus32kidneycortexGlomerulonephritis (mesangioproliferative glomerulonephritis)3.980.0061RNA microarray23192593

Compile date 08-10-2018© iMODE-CKD consortium