CKDdb-logoCKDdb - Molecule ID A6817

geneAP5Z1, SPG48
nameAP-5 complex subunit zeta-1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
AP5Z1_HUMANO43299ENSG000002428029907Hs.558440613647, 613653

Functions and classifications

GOC:AP-5 adaptor complex, C:AP-type membrane coat adaptor complex, C:nucleolus, P:cell death, P:double-strand break repair via homologous recombination, P:endosomal transport, P:protein transport
UniProtAlternative splicing, Complete proteome, Cytoplasm, DNA damage, DNA repair, Hereditary spastic paraplegia, Neurodegeneration, Nucleus, Polymorphism, Protein transport, Reference proteome, Transport
PADBtransport, storage, endocytosis, exocytosis, vesicles

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.360.0000312RNA microarray19698090
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)3.780.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium