CKDdb-logoCKDdb - Molecule ID A673B

geneALS2CR4, TMEM237
nameAmyotrophic lateral sclerosis 2 chromosomal region candidate gene 4 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
TM237_HUMANQ96Q45ENSG0000015575565062Hs.12319614423, 614424

Functions and classifications

GOC:ciliary transition zone, C:integral component of membrane, P:cilium assembly, P:regulation of Wnt signaling pathway, C:integral to membrane, P:regulation of Wnt receptor signaling pathway
UniProtAlternative splicing, Cell projection, Ciliopathy, Cilium, Cilium biogenesis/degradation, Complete proteome, Joubert syndrome, Membrane, Polymorphism, Reference proteome, Transmembrane, Transmembrane helix
PADBDEV: development, cell growth, differentiation, morphogenesis

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.493.85E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium