CKDdb-logoCKDdb - Molecule ID A6638

geneAGPAT6, GPAT4, UNQ551/PRO1108
nameGlycerol-3-phosphate acyltransferase 4
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GPAT4_HUMANQ86UL3ENSG00000158669137964Hs.355753608143

Functions and classifications

GOC:endoplasmic reticulum membrane, C:integral component of membrane, F:glycerol-3-phosphate O-acyltransferase activity, P:acyl-CoA metabolic process, P:CDP-diacylglycerol biosynthetic process, P:diacylglycerol metabolic process, P:fatty acid metabolic process, P:glandular epithelial cell maturation, P:lactation, P:phosphatidic acid biosynthetic process, P:phosphatidylcholine biosynthetic process, P:regulation of multicellular organism growth, P:triglyceride biosynthetic process, "C:endoplasmic reticulum, F:transferase activity, transferring acyl groups, P:triglyceride biosynthetic process", "F:transferase activity, transferring acyl groups, P:metabolic process", C:endoplasmic reticulum, C:integral to membrane, "F:transferase activity, transferring acyl groups"
UniProtAcyltransferase, Complete proteome, Direct protein sequencing, Endoplasmic reticulum, Glycoprotein, Lipid biosynthesis, Lipid metabolism, Membrane, Phospholipid biosynthesis, Phospholipid metabolism, Reference proteome, Signal, Transferase, Transmembrane, Transmembrane helix
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)5.40.007677RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)6.430.013999RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium