CKDdb-logoCKDdb - Molecule ID A6578

geneAMT, GCST
nameAminomethyltransferase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
GCST_HUMANP48728ENSG00000145020275Hs.102238310, 605899

Functions and classifications

GOC:mitochondrion, F:aminomethyltransferase activity, F:transaminase activity, P:glycine catabolic process, P:methylation, C:cytoplasm
UniProt3D-structure, Alternative splicing, Aminotransferase, Complete proteome, Disease mutation, Mitochondrion, Reference proteome, Transferase, Transit peptide, Methyltransferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.470.000154RNA microarray19698090
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.541.98E-05RNA microarray20019191
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.480.00591RNA microarray24569379
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)9.340.005591RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium