CKDdb-logoCKDdb - Molecule ID A6500

geneBrip1, Bach1, Fancj
nameFanconi anemia group J protein homolog
speciesMus musculus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
FANCJ_MOUSEQ5SXJ3ENSMUSG00000034329237911Mm.186143114480, 227650, 605882, 609054

Functions and classifications

GOC:cytoplasm, C:nuclear membrane, F:4 iron, 4 sulfur cluster binding, F:ATP binding, F:ATP-dependent DNA helicase activity, F:DNA binding, F:metal ion binding, P:DNA repair, P:regulation of transcription from RNA polymerase II promoter, C:nucleus, F:hydrolase activity, acting on acid anhydrides
UniProt4Fe-4S, Acetylation, ATP-binding, Complete proteome, DNA damage, DNA repair, Helicase, Hydrolase, Iron, Iron-sulfur, Metal-binding, Nucleotide-binding, Nucleus, Phosphoprotein, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp21411733bMus musculus11macrophageF4/80hi cellsGlomerulonephritis (lupus nephritis)0.490.001cDNA microarray21411733
Exp24172336Mus musculus6kidneycortexAKI (AKI)10000.0062007LC-MS/MS24172336
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.292.16E-03RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.321.21E-03RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.130.012805RNA microarray26317775
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.160.01415RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium