CKDdb-logoCKDdb - Molecule ID A6215

geneCSAD, pcap, CSD
nameCysteine sulfinic acid decarboxylase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
CSAD_HUMANQ9Y600ENSG0000013963151380Hs.279815

Functions and classifications

GOF:pyridoxal phosphate binding, F:sulfinoalanine decarboxylase activity, P:cellular nitrogen compound metabolic process, P:sulfur amino acid catabolic process, P:taurine biosynthetic process, P:carboxylic acid metabolic process, F:carboxy-lyase activity
UniProt3D-structure, Alternative splicing, Complete proteome, Decarboxylase, Lyase, Pyridoxal phosphate, Reference proteome, Lectin
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17003339aMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.31< 0.05cDNA microarray17003339
Exp17003339bMus musculus24kidneyglomeruliDiabetes (diabetic nephropathy)0.56< 0.05cDNA microarray17003339
Exp17881425Mus musculus12urinewholeGlomerulonephritis (focal segmental glomerulosclerosis)  MALDI-TOF-MS17881425
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.30.000000328RNA microarray19698090
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.323.00E-04Nano RP-LC, MALDI-TOF22061828
Exp23505438aHomo sapiens kidneyproximal tubular cellsDiabetes (diabetic nephropathy)0.720.036cDNA microarray23505438
Exp23757392aRattus norvegicus17kidneywholeDiabetes (diabetic nephropathy)0.4< 0.05RNA-seq23757392
Exp23809614aHomo sapiens83bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.23.73E-13RNA microarray23809614
Exp23809614bHomo sapiens32bloodwholeChronic_Renal_Insufficiency (End-stage renal failure)0.131.27E-11RNA microarray23809614
Exp24569379Mus musculus kidneyendothelial cellsAKI (AKI)0.390.000869RNA microarray24569379
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.221.03E-05RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium