CKDdb-logoCKDdb - Molecule ID A616E

geneBTG2, PC3
nameBTG2 protein
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
BTG2_HUMANP78543ENSP000002905517832Hs.519162601597

Functions and classifications

GOF:RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription, P:anterior/posterior pattern specification, P:associative learning, P:central nervous system neuron development, P:dentate gyrus development, P:DNA repair, P:negative regulation of cell proliferation, P:negative regulation of neural precursor cell proliferation, P:negative regulation of neuron apoptotic process, P:negative regulation of translation, P:neuron projection development, P:positive regulation of nuclear-transcribed mRNA poly(A) tail shortening, P:protein methylation, P:response to electrical stimulus, P:response to mechanical stimulus, P:response to organic cyclic compound, P:response to peptide hormone, P:skeletal muscle cell differentiation, P:transcription from RNA polymerase II promoter, P:negative regulation of apoptotic process, P:response to peptide hormone stimulus
UniProt3D-structure, Complete proteome, Phosphoprotein, Polymorphism, Reference proteome, Transcription, Transcription regulation
PADBTF: transcription and translation, gene regulation

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)1.528.24E-06RNA microarray20019191

Compile date 08-10-2018© iMODE-CKD consortium