CKDdb-logoCKDdb - Molecule ID A6011

geneCBR3
nameCarbonyl reductase [NADPH] 3
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CBR3_HUMANO75828ENSG00000159231874Hs.154510603608

Functions and classifications

GOC:cytosol, C:nucleus, F:3-keto sterol reductase activity, F:carbonyl reductase (NADPH) activity, F:NADPH binding, P:phylloquinone catabolic process, F:oxidoreductase activity, P:oxidation-reduction process, F:nucleotide binding
UniProt3D-structure, Complete proteome, Cytoplasm, NADP, Oxidoreductase, Polymorphism, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp20019191Homo sapiens18kidneyglomeruliNephrosclerosis (glomerulosclerosis)3.073.23E-06RNA microarray20019191
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)2.690.0299538RNA microarray23935909
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)00.025042862LC-MS/MS24316357

Compile date 08-10-2018© iMODE-CKD consortium