CKDdb-logoCKDdb - Molecule ID A600F

geneCAPN8, NCL2
nameCalpain-8
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGene
CAN8_HUMANA6NHC0ENSG00000203697388743Hs.291487

Functions and classifications

GOC:Golgi apparatus, F:calcium ion binding, F:calcium-dependent cysteine-type endopeptidase activity, P:proteolysis, C:intracellular
UniProtAutocatalytic cleavage, Calcium, Complete proteome, Cytoplasm, Golgi apparatus, Hydrolase, Metal-binding, Protease, Reference proteome, Repeat, Thiol protease
PADBENZ: enzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.298.97E-04RNA microarray26317775
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)4.143.04E-03RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium