CKDdb-logoCKDdb - Molecule ID A599F

geneCAPN6, CALPM, CANPX
nameCalpain 6
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CAN6_HUMANQ9Y6Q1ENSG00000077274827Hs.496593300146

Functions and classifications

GOC:perinuclear region of cytoplasm, C:spindle microtubule, F:calcium-dependent cysteine-type endopeptidase activity, F:microtubule binding, P:microtubule bundle formation, P:proteolysis, P:regulation of cytoskeleton organization, C:microtubule, C:intracellular
UniProtComplete proteome, Cytoplasm, Cytoskeleton, Microtubule, Polymorphism, Reference proteome
PADBCell shape (cytoskeleton, cell adhesion, morphology, cell junction, cellular structures, extracellular matrix)

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp17183245Homo sapiens24kidneyproximal tubuleproteinuria (proteinuric nephropathies)5.24< 0.05cDNA microarrays17183245
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.430.00209RNA microarray19698090
Exp21752957aHomo sapiens22kidneytubuliDiabetes (diabetic kidney disease)22.56< 0.05RNA microarray21752957
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.280.0169746RNA microarray23935909
Exp26317775bHomo sapiens8kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.230.014185RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium