CKDdb-logoCKDdb - Molecule ID A5981

geneCAT
nameCatalase
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CATA_HUMANP04040ENSG00000121691847Hs.502302115500, 614097

Functions and classifications

GOC:cytosol, C:endoplasmic reticulum, C:Golgi apparatus, C:lysosome, C:mitochondrial intermembrane space, C:peroxisomal matrix, C:peroxisomal membrane, C:plasma membrane, F:aminoacylase activity, F:catalase activity, F:heme binding, F:metal ion binding, F:NADP binding, F:protein homodimerization activity, P:aerobic respiration, P:cellular response to growth factor stimulus, P:cholesterol metabolic process, P:hemoglobin metabolic process, P:hydrogen peroxide catabolic process, P:kidney development, P:menopause, P:negative regulation of apoptotic process, P:negative regulation of NF-kappaB transcription factor activity, P:positive regulation of cell division, P:positive regulation of NF-kappaB transcription factor activity, P:positive regulation of phosphatidylinositol 3-kinase signaling, P:protein homotetramerization, P:purine nucleobase metabolic process, P:purine nucleotide catabolic process, P:response to hyperoxia, P:response to hypoxia, P:response to vitamin E, P:triglyceride metabolic process, P:ureteric bud development, P:UV protection, P:positive regulation of phosphatidylinositol 3-kinase cascade
UniProt3D-structure, Acetylation, Complete proteome, Direct protein sequencing, Heme, Hydrogen peroxide, Iron, Metal-binding, Mitogen, NADP, Oxidoreductase, Peroxidase, Peroxisome, Phosphoprotein, Reference proteome
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19099603cMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.340.02cDNA microarray19099603
Exp19099603dMus musculus6kidneywholePolycystic_Kidney_Disease (Autosomal Dominant Polycystic kidney disease)0.390cDNA microarray19099603
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.080.000000821RNA microarray19698090
Exp20093355Homo sapiens33kidney Fibrosis (Interstitial fibrosis and tubular atrophy)down MS/MS, LTQ LX linear ion trap20093355
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.247.20E-05Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.276.50E-04Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.289.70E-05Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.292.80E-04Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.293.00E-04Nano RP-LC, MALDI-TOF22061828
Exp22061828Rattus norvegicus kidney Gentamicin_induced (Gentamicin-induced nephropathy)0.347.50E-04Nano RP-LC, MALDI-TOF22061828
Exp23935909Homo sapiens24bloodmonocytesChronic_Renal_Insufficiency (Chronic kidney disease)0.180.0488141RNA microarray23935909
Exp24316357Rattus norvegicus kidneyproximal tubule cellsureteral_obstruction (kidney obstruction in vitro model)0.370.000468522LC-MS/MS24316357

Compile date 08-10-2018© iMODE-CKD consortium