CKDdb-logoCKDdb - Molecule ID A5979

geneCasp7
nameCaspase 7
speciesRattus norvegicus

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CASP7_HUMANO88550ENSRNOG0000001683664026Rn.53995601761

Functions and classifications

GOC:cytosol, C:intracellular membrane-bounded organelle, F:cysteine-type endopeptidase activity, F:cysteine-type peptidase activity, P:aging, P:apoptotic process, P:execution phase of apoptosis, P:proteolysis, F:aspartic-type endopeptidase activity, P:heart development, P:induction of apoptosis, P:positive regulation of neuron apoptotic process, P:protein processing, P:release of cytochrome c from mitochondria, P:response to UV, C:cytosol, C:intracellular membrane-bounded organelle, C:nucleus, F:aspartic-type endopeptidase activity, F:cysteine-type endopeptidase activity, F:cysteine-type endopeptidase activity involved in apoptotic process, F:cysteine-type peptidase activity, P:aging, P:apoptotic process, P:execution phase of apoptosis, P:heart development, P:positive regulation of neuron apoptotic process, P:protein processing, P:proteolysis, P:release of cytochrome c from mitochondria, P:response to UV
UniProtHydrolase, Protease, Thiol protease, Zymogen, Complete proteome, Reference proteome,
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp23291264aRattus norvegicus kidneyproximal tubulecisplatin_induced (cisplatin-induced nephrotoxicity)2.50.0029759RNA microarray23291264
Exp26317775aHomo sapiens53kidneybiopsy specimensChronic_Renal_Insufficiency (CKD)0.437.62E-04RNA microarray26317775

Compile date 08-10-2018© iMODE-CKD consortium