CKDdb-logoCKDdb - Molecule ID A5977

geneCARM1, PRMT4
nameHistone-arginine methyltransferase CARM1
speciesHomo sapiens

Molecule reference

SwissProtUniProtEnsEMBLGeneIDUniGeneOMIM
CARM1_HUMANQ86X55ENSG0000014245310498Hs.323213603934

Functions and classifications

GOC:cytosol, C:nucleoplasm, F:beta-catenin binding, F:histone acetyl-lysine binding, F:histone methyltransferase activity (H3-R17 specific), F:ligand-dependent nuclear receptor transcription coactivator activity, F:protein-arginine omega-N asymmetric methyltransferase activity, F:transcription regulatory region DNA binding, P:cellular lipid metabolic process, P:endochondral bone morphogenesis, P:histone H3-R2 methylation, P:intracellular estrogen receptor signaling pathway, P:negative regulation of protein binding, P:pathogenesis, P:positive regulation of cell proliferation, P:positive regulation of fat cell differentiation, P:regulation of growth plate cartilage chondrocyte proliferation, P:regulation of intracellular estrogen receptor signaling pathway, P:regulation of transcription, DNA-templated, P:response to cAMP, P:small molecule metabolic process, P:transcription, DNA-templated, P:viral process, P:intracellular steroid hormone receptor signaling pathway, P:regulation of transcription, DNA-dependent, P:transcription, DNA-dependent, P:virus-host interaction, F:methyltransferase activity, P:protein methylation
UniProt3D-structure, Acetylation, Alternative splicing, Chromatin regulator, Complete proteome, Cytoplasm, Host-virus interaction, Methylation, Methyltransferase, Nucleus, Phosphoprotein, Reference proteome, S-adenosyl-L-methionine, Transcription, Transcription regulation, Transferase
PADBenzyme, enzymatic properties

Studies, tissues and diseases

Study IDSpeciesNTissue / SourceCompartmentDiseaseFold change in diseaseP-valueDetectionPubMed/DOI
Exp19698090bHomo sapiens25bloodmononuclear cellsDialysis (hemodialysis)0.30.00000654RNA microarray19698090

Compile date 08-10-2018© iMODE-CKD consortium